Men & NAD+

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in all living cells, playing a crucial role in energy metabolism and cellular functions. Research indicates that NAD+ levels decline with age, leading to interest in supplementation to mitigate age-related health issues. While extensive human studies are limited, emerging evidence suggests potential benefits of NAD+ supplementation for men in specific areas:

 

Muscle Function and Physical Performance

A study involving healthy older men assessed the impact of NMN supplementation on muscle function. Results demonstrated that NMN administration elevated blood NAD+ levels and positively influenced muscle performance metrics, suggesting potential benefits for age-related muscle decline (Igarashi et al., 2022).

Supplementation decreased oxidative stress and improved physical performance in older participants (Dolopikou et al., 2019).

 

Improved Metabolism

Overweight and obese participants aged 45+ years were administered an NAD precursor. Results indicated significant improvements in body weight, diastolic blood pressure, total cholesterol, low-density lipoprotein cholesterol and nonhigh-density lipoprotein cholesterol when compared to a placebo (Pencina et al., 2023).


Cognitive Function

Preliminary studies suggest that NAD+ supplementation may support cognitive health by enhancing neuronal function and protecting against neurodegenerative processes (Braidy et al., 2019).

 

Cardiovascular Health

NAD+ can play a role in cardiovascular health by influencing metabolic processes and reducing oxidative stress. Maintaining NAD+ levels may support heart health and mitigate age-related cardiovascular issues by reducing inflammation (Zhang et al., 2021).


 

*These supplements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.